Streptococcus viridans Endocarditis Affecting All Four Valves

Role of the vegetation in experimental Streptococcus viridans endocarditis.

This study examines the role of the vegetation in catheter-induced experimental endocarditis in predisposing to bacterial colonization of cardiac valves and in influencing the course of the disease and response to penicillin therapy. Platelet-fibrin vegetations developed at areas of valvular trauma and were colonized when Streptococcus viridans were injected intravenously. Pretreatment with war...

Trovafloxacin treatment of viridans group Streptococcus experimental endocarditis.

The activity of trovafloxacin was compared with those of vancomycin and penicillin in a model of Streptococcus sanguis species group (trovafloxacin MIC, 0.125 microg/ml) and Streptococcus mitis species group (trovafloxacin MIC, 0.125 microg/ml) experimental endocarditis. Rabbits with catheter-induced aortic valve vegetations were given no treatment, trovafloxacin at 15 mg/kg of body weight thre...

An immunofluorescent method for detecting antibodies against viridans streptococci in Streptococcus viridans endocarditis.

Serum was collected one to three months after the onset of symptoms from eight endocarditis cases and from another endocarditis case about three weeks after the onset of symptoms (case 8 in Table). Endocarditis was proven in each case clinically and by numerous sets of blood -cultures that yielded growth of viridans streptococci. Three positive standard reference sera, obtained from patients wi...

Streptococcus sanguinis Endocarditis Involving All Valves in a Patient with Ventricular Septal Defect

Rheumatic involvement of all four cardiac valves.

Rheumatic involvement of all four heart valves is rare. A 35 year old woman presented with gradually progressive exertional dyspnoea for the preceding 10 years. On evaluation she was in atrial fibrillation with congestive heart failure. Clinical examination found evidence of stenosis of the mitral aortic and tricuspid valves with a history of rheumatic fever in childhood. Transthoracic echocard...